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82 Allergen Detection Test (GC-MS/MS)

950.00

Reliable Allergen Testing for Cosmetics, Fragrance, and Home Products

Fragrance allergens are at the heart of EU cosmetic and chemical regulations. Whether they occur naturally in essential oils or are part of synthetic fragrance blends, their presence needs to be measured and declared with precision. Our laboratory offers advanced detection of 82 regulated fragrance allergens using GC-MS/MS technology. This service ensures you stay compliant with EU Cosmetic Regulation 1223/2009, CLP, and IFRA Standards, while also protecting consumer safety and brand reputation.

Why Allergen Testing Matters

Across Europe, companies must declare allergens on cosmetic and detergent labels when concentrations exceed regulatory thresholds. For cosmetics, this means anything above 0.001% in leave-on products or 0.01% in rinse-off products must be listed.

In the past, only 26 allergens needed disclosure, but the list has now expanded to 82 substances. This change affects everyone in the supply chain — from raw material suppliers to brands and safety assessors — and makes reliable allergen testing more important than ever.

What We Test

The method covers the full spectrum of regulated fragrance allergens, including familiar compounds such as Linalool, Citral, Geraniol, Eugenol, Limonene, Coumarin, Benzyl Benzoate, and Farnesol. These substances are often naturally present in essential oils but also appear in synthetic blends. Because their levels vary by source and batch, testing is the only way to ensure accurate disclosure.

✔ A complete list of all 82 allergens is available upon request.

Technology We Use: GC-MS/MS

Our laboratory relies on Gas Chromatography with Tandem Mass Spectrometry (GC-MS/MS), the gold standard for fragrance allergen detection. This method separates complex fragrance mixtures into their individual components and identifies them with high precision.

What makes GC-MS/MS the preferred choice:

  • Detects allergens at very low concentrations (ppm and ppb range).

  • Provides quantitative results rather than simple “present/absent” findings.

  • Works equally well for raw materials and finished products.

In short, GC-MS/MS allows us to deliver data you can rely on for compliance and formulation decisions.

Applications of the 82 Allergen Test

Our allergen detection service is designed for a wide range of industries. Cosmetic brands use it to prepare their CPSR and product labels. Candle and diffuser makers depend on it for IFRA compliance and safe consumer labelling. Raw material suppliers benefit from verified data when selling essential oils and fragrance blends.

Other relevant applications include:

  • Cosmetics: perfumes, lotions, hair care, skincare, makeup.

  • Candles and home fragrance: ensuring safe allergen disclosures.

  • Detergents and cleaning products: meeting CLP and Detergent Regulation standards.

Benefits for Your Business

Accurate allergen testing offers more than just compliance. It provides independent verification of supplier documentation, ensures your product information is trustworthy, and supports smooth approval by safety assessors.

Key advantages include:

  • Verified compliance with EU allergen disclosure rules.

  • Essential data for Cosmetic Product Safety Reports (CPSR).

  • Support for creating IFRA Conformity Certificates.

  • Transparent allergen declarations that build consumer confidence.

How the Process Works

  1. Choosing laboratory test
    • You purchase the laboratory test through our website.
  2. Access to secure Portal
    • After purchase, you will gain access to our secure portal where you can complete the intake.
  3. Scedule laboratory test
    • Complete all requested information about your product and upload relevant documentation.
  4. Send Samples
    • Send physical samples of your product to our laboratory. When you scedule your lab test in the portal the safety assessor will request the number of samples. It depends on your product and packaging.
  5. Laboratory tests
    • We performlaboratory tests.
  6. Results
    • Our safety reviewer prepares the laboratory test results, uploads the report to the portal and notifies you.

Who Should Use This Test

This service is essential for:

  • Cosmetic brands launching products in the EU/EEA.

  • Fragrance oil suppliers validating natural or synthetic blends.

  • Candle and diffuser makers needing allergen sheets and IFRA compliance.

  • Safety assessors and toxicologists who require verified analytical data.

Why Testing Makes a Difference

Consider lavender essential oil. It naturally contains compounds such as linalool and linalyl acetate, but concentrations vary significantly depending on harvest and origin. Without testing, it’s impossible to know whether the allergen levels exceed regulatory thresholds.

Synthetic fragrance blends can be even more complex, often containing multiple allergens in varying proportions. GC-MS/MS testing ensures these details are measured and reported accurately, protecting both compliance and consumer safety.

Beyond Testing

We also provide follow-up services to help you act on the results:

  • Preparation of IFRA Certificates.

  • Creation of allergen declaration sheets in multiple EU languages.

  • Toxicological pre-screening for formulations.

  • Full compliance packages including CPSR, PCN, UFI, and CLP support.

82 Fragrance Allergens (EU, Annex III)

Here’s the full list of the 82 fragrance allergens that are included in the new expanded EU Cosmetic Regulation Annex III.

# INCI Name CAS Number Typical Source Regulatory Status*
1 Alpha-Isomethyl Ionone 127-51-5 Synthetic violet-like fragrance Restricted allergen
2 Amyl Cinnamal 122-40-7 Jasmine, synthetic Restricted allergen
3 Amylcinnamyl Alcohol 101-85-9 Jasmine, synthetic Restricted allergen
4 Anisyl Alcohol 105-13-5 Anise oil, synthetic Restricted allergen
5 Benzyl Alcohol 100-51-6 Balsams, jasmine Restricted allergen
6 Benzyl Benzoate 120-51-4 Balsams, essential oils Restricted allergen
7 Benzyl Cinnamate 103-41-3 Balsam of Peru Restricted allergen
8 Benzyl Salicylate 118-58-1 Ylang-ylang, synthetic Restricted allergen
9 Cinnamal 104-55-2 Cinnamon oil Restricted allergen
10 Cinnamyl Alcohol 104-54-1 Cinnamon leaves Restricted allergen
11 Citral 5392-40-5 Lemongrass, citrus oils Restricted allergen
12 Citronellol 106-22-9 Rose, geranium Restricted allergen
13 Coumarin 91-64-5 Tonka beans Restricted allergen
14 Eugenol 97-53-0 Clove oil Restricted allergen
15 Farnesol 4602-84-0 Rose oil, orange blossom Restricted allergen
16 Geraniol 106-24-1 Rose, palmarosa, citronella Restricted allergen
17 Hexyl Cinnamal 101-86-0 Jasmine-like scent Restricted allergen
18 Hydroxycitronellal 107-75-5 Lily of the valley, synthetic Restricted allergen
19 Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde (Lyral) 31906-04-4 Synthetic Banned (still monitored)
20 Isoeugenol 97-54-1 Ylang-ylang, clove Restricted allergen
21 Limonene 5989-27-5 Citrus peel oils Restricted allergen
22 Linalool 78-70-6 Lavender, coriander Restricted allergen
23 Methyl 2-Octynoate (Methyl Heptine Carbonate) 111-12-6 Synthetic, fruity-green Restricted allergen
24 Evernia Prunastri Extract (Oak Moss) 90028-68-5 Lichen extract Restricted allergen
25 Evernia Furfuracea Extract (Tree Moss) 90028-67-4 Lichen extract Restricted allergen
26 2-(4-tert-Butylbenzyl)propionaldehyde (Lilial) 80-54-6 Synthetic floral Banned (still monitored)
27 Allyl Heptanoate 142-19-8 Pineapple-like, synthetic Restricted allergen
28 Allyl Hexanoate 123-68-2 Pineapple, synthetic Restricted allergen
29 Allyl Phenoxyacetate 7493-74-5 Sweet floral, synthetic Restricted allergen
30 Allyl 3-Cyclohexylpropionate 2705-87-5 Fruity, synthetic Restricted allergen
31 Anethole 4180-23-8 Anise, fennel Restricted allergen
32 Benzaldehyde 100-52-7 Almonds, cinnamon oil Restricted allergen
33 Benzyl Acetate 140-11-4 Jasmine, ylang-ylang Restricted allergen
34 Benzyl Formate 104-57-4 Fruity, balsamic Restricted allergen
35 Benzyl Isoeugenol 120-11-6 Synthetic Restricted allergen
36 beta-Caryophyllene 87-44-5 Clove, copaiba, cannabis Restricted allergen
37 Musk T (Bicyclononalactone) 116-66-5 Synthetic musk Restricted allergen
38 Butylphenyl Methylpropional (Lilial duplicate) 80-54-6 Synthetic Banned
39 Camphor 76-22-2 Camphor tree oil Restricted allergen
40 Cananga Oil 68606-83-7 Ylang-ylang type Restricted allergen
41 Carvone 2244-16-8 Caraway, spearmint Restricted allergen
42 Cedrol 77-53-2 Cedarwood oils Restricted allergen
43 Cinnamyl Anthranilate 87-29-6 Synthetic Restricted allergen
44 Cis-3-Hexenyl Salicylate 65405-77-8 Green, leafy scent Restricted allergen
45 Citronellyl Acetate 150-84-5 Geranium, citronella Restricted allergen
46 Citronellyl Nitrile 51566-62-2 Synthetic Restricted allergen
47 Cyclamen Aldehyde 103-95-7 Synthetic floral Restricted allergen
48 Dihydroisojasmone 17283-81-7 Jasmine-like, synthetic Restricted allergen
49 Dimethyl Anthranilate 85-91-6 Synthetic, fruity Restricted allergen
50 Ethyl Vanillin 121-32-4 Vanilla-like, synthetic Restricted allergen
51 Eugenyl Acetate 93-28-7 Clove, cinnamon leaf Restricted allergen
52 Florhydral (3-(4-tert-Butylphenyl)-2-methylpropanal) 80-54-6 Synthetic Restricted allergen
53 Geranyl Acetate 105-87-3 Rose, citronella Restricted allergen
54 Helional (3-(4-Methylphenyl)propanal) 1205-17-0 Synthetic Restricted allergen
55 Hexyl Salicylate 6259-76-3 Synthetic floral Restricted allergen
56 Indole 120-72-9 Jasmine, orange blossom Restricted allergen
57 Isoamyl Salicylate 87-20-7 Jasmine-like, synthetic Restricted allergen
58 Isobutylphenyl Propional 125-68-8 Synthetic Restricted allergen
59 Isopulegol 89-79-2 Mint oils Restricted allergen
60 Linalyl Acetate 115-95-7 Lavender, bergamot Restricted allergen
61 Methyl 2-Nonynoate 111-80-8 Synthetic, fruity-green Restricted allergen
62 Methyl Chavicol (Estragole) 140-67-0 Basil, tarragon Restricted allergen
63 Methyl Eugenol 93-15-2 Basil, ylang-ylang Restricted allergen
64 Methyl Iso-Eugenol 93-16-3 Synthetic Restricted allergen
65 Methyl Salicylate 119-36-8 Wintergreen oil Restricted allergen
66 Methyl-N-methyl Anthranilate 85-91-6 Synthetic Restricted allergen
67 Nerol 106-25-2 Rose, lemongrass Restricted allergen
68 Ocimene 13877-91-3 Citrus, mint oils Restricted allergen
69 p-Mentha-1,4-dien-7-ol 499-75-2 Mint oils Restricted allergen
70 p-Mentha-1,4-dien-7-yl Acetate 67674-46-8 Synthetic Restricted allergen
71 Phenyl Acetaldehyde 122-78-1 Hyacinth, rose Restricted allergen
72 Phenylacetic Acid 103-82-2 Honey, cocoa Restricted allergen
73 Phenylacetonitrile 140-29-4 Synthetic Restricted allergen
74 Phenylpropyl Alcohol 122-97-4 Synthetic floral Restricted allergen
75 Precyclemone B 68155-66-8 Synthetic musk Restricted allergen
76 Rose Ketones (Ionones, Damascones, Damascenones) Various Rose oil, synthetic Restricted allergen
77 Sclareolide 564-20-5 Clary sage Restricted allergen
78 Terpineol 8000-41-7 Pine, petitgrain Restricted allergen
79 Terpinyl Acetate 8007-35-0 Pine oils Restricted allergen
80 Tetrahydro Linalool 18479-58-8 Synthetic Restricted allergen
81 Tetrahydro Myrcenol 18479-57-7 Synthetic Restricted allergen
82 Vanillin 121-33-5 Vanilla pods, synthetic Restricted allergen

* Regulatory Status: “Restricted allergen” = must be declared above thresholds (0.001% leave-on / 0.01% rinse-off). “Banned” = no longer permitted but still included in analytical screening.